This study will increase our understanding of the impact of gestational diabetes mellitus on cardiometabolic health during foetal and neonatal periods. A long-term follow-up of children is planned. MySweetHeart Cohort is linked to MySweetHeart Trial (/ct2/show/ NCT02890693), a randomised controlled trial assessing the effect of a multidimensional interdisciplinary lifestyle and psychosocial intervention to improve the cardiometabolic and mental health of women with GDM and their offspring. An echocardiography will be performed to assess cardiac structure and function 2–7 days after birth carotid intima-media thickness will be also measured to assess vascular structure. At birth, maternal and neonatal characteristics will be assessed. Between the 30th and 34th weeks of gestation, a foetal echography will be performed to assess the foetal cardiac structure and function, the fetomaternal circulation and the hepatic volume. At inclusion, a baseline assessment of the mothers will be conducted through means of self-report questionnaires, a researcher-administrated interview, blood pressure and anthropometric measurements, and a maternal blood sampling. Methods and analysis This is a cohort study of 100 offspring of women with GDM and 100 offspring of women without GDM.
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